Lady Macbeth is more determined than ever for the murder plan to proceed.She has drugged the King's guards and, hearing Macbeth, worries he may not have been able to go through with the act. She says she would've killed Duncan herself, if he hadn't looked so much like her father in his sleep. (Apparently, now she's all family values.Macbeth enters with bloody hands.Macbeth says two people woke up while he was in the act. One cried, "Murder!" but they both went back to sleep after saying their prayers. Macbeth is disturbed that he couldn't say "Amen" when they said, "God bless us," as he could have used the blessing, given how he recently damned his soul by killing the King.Lady Macbeth employs the "If you don't think about, it will go away" theorem, but Macbeth is still clearly disturbed at having killed a sleeping old man for his own selfish gain. He also worried because he thinks he heard voices saying things like "Macbeth does murder sleep!" Lady Macbeth tries to get her husband to focus on the matter at hand, which is framing the King's attendants. He won't do it himself, so she takes the daggers from him, smears the attendants with Duncan's blood, and plants the weapons.As Macbeth philosophizes about his guilty hands, Lady Macbeth comes back, having done her part.She hears a knock at the door, and hurries Macbeth to bed so that 1) they don't look suspicious, and 2) they can do a little washing up before all the "Oh no! The king is dead" morning hullabaloo.Macbeth regrets killing Duncan – he says he wishes that all the knocking at the door would "wake Duncan" from his eternal sleep.